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10 Industries That Can’t Operate Without CIP

September 26, 2025 by BPM Team

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Inspector in a mask and a scrub stands with a folder-tablet in his hands at the dairy plant

Do you know what a milk processing company and a pharmaceutical company have in common? They both need high-grade Clean-In-Place equipment (CIP) to make sure that their products are compliant with their respective regulatory bodies. 

Before CIP systems, these units had to take apart their vessels and pipes and thoroughly clean them after each cycle. With CIP systems, they can now run more efficiently.

For industries where safety and consistency are non-negotiable, clean-in-place equipment really helps in flushing all their equipment with a controlled cleaning cycle. This helps in saving time, reducing errors, and keeping the product safe.

If you are a manufacturer wondering whether your industry needs a CIP system, this guide is for you. We have a list of 10 industries where CIP systems are used, detailing the exact role they play in making sure that the finished product is of the highest quality and is compliant.  

1. Dairy and Beverages

There’s a lot that can go wrong with milk or juices. They are easy to spoil, and once spoilt, they may render your entire batch unsellable. Even a small amount of residue left inside a tank or a pipeline could lead to bacterial growth and pose severe health risks. 

A CIP system in these facilities ensures that every surface that touches the product is sanitised without forcing them to carry out manual cleaning cycles.

2. Food Processing

It would take hours to manually remove residue from packaged sauces, soups, or syrups, and there would be no way to know if you had cleaned every nook and cranny. With a CIP machine, you can modify the cleaning solution and rinse cycle flow according to your product, ensuring that your pipes and vessels are free of residue.

These systems help food companies manufacture multiple products using the same vessels because they can switch from one product to another while maintaining the strict hygiene standards.

3. Pharmaceuticals

Our medications contain very potent chemicals in controlled amounts that work together to support us. It could be extremely dangerous if there is a difference in the quantity of chemicals or an unidentified chemical compound due to residue left in the vessels. 

Cross-contamination could also land pharmaceutical companies in regulatory trouble, which can be solved easily by GMP-validated CIP equipment. In most regulated pharma environments, CIP is essential to ensure compliance. 

4. Nutraceuticals

Manufacturing of supplements, vitamins, and power drinks comes under the same scrutiny as a pharmaceutical or a food company. These manufacturing plants need to comply with all the hygiene regulations and standards so that the customers get clear proof of quality.

A CIP system in these companies helps them achieve repeatable, consistent cleaning cycles so that they can make multiple batches and get the same quality of products each time.

5. Biotechnology

Many biotech companies carry out highly sensitive biological processes such as fermentation or analysing cell cultures. A single contamination in these processes could cost the company millions and also affect their research. CIP gives biotech companies the ability to maintain sterile conditions across complex systems without having to disassemble the equipment and wear it out. 

6. Brewing

The quality of beer depends on precision at every stage, and even the smallest residue left behind can spoil the flavour of an entire batch. Whether you run a small taproom or a large-scale brewery, Clean-in-Place (CIP) equipment is essential for maintaining hygiene. These systems ensure fermenters, tanks and pipelines are thoroughly cleaned between batches, protecting both taste and consistency.

CIP equipment also offers flexibility. Through a central control panel, you can adjust the flow and settings to effectively remove residues such as yeast or sugar, keeping your brewing equipment spotless and your beer at its best.

7. Edible Oils and Fats

Cleaning machinery used to produce edible oils, butter and other fat-based products can be especially challenging due to greasy residues. CIP systems are designed to handle this by circulating heated caustic solutions through pipes and holding tanks, effectively dissolving stubborn fat layers. This process is critical to keeping production lines free from rancidity and ensuring product quality.

8. Cosmetics and Personal Care

Products such as creams, gels and lotions often contain waxes or oils that can cling to equipment. Because these items are applied directly to the skin, preventing cross-contamination is essential. CIP systems in these facilities use heated cleaning solutions and specialised emulsifiers to break down residues, ensuring hygiene and safety throughout the manufacturing process.

9. Medical Devices

Manufacturers of syringes, catheters, implants and other medical devices must follow strict GMP standards and maintain sterile environments. CIP systems play a vital role in keeping moulding machines, coating systems and cleanroom piping contamination-free. In many cases, CIP is followed by SIP (Sterilisation-in-Place) to ensure microbial control.

10. Speciality Chemicals

In the production of speciality chemicals, even minor contamination can ruin entire batches or compromise product performance. CIP systems here often rely on customised chemical cleaning solutions tailored to the products being manufactured. This helps keep reactors, mixers and pipelines clean between runs while reducing the risk of costly recalls.

Why This Matters For Businesses

It’s easy to think of cleaning as a background task. But when it comes to some critical industries, a cleaning system and its equipment should be one of the first things to consider. All of these industries have made a commitment to provide the very best to their customers, and avoiding cross-contamination or product recalls plays a huge role in gaining people’s trust. 

As industries grow and regulations tighten, CIP will be used in more industries because it is one of the systems that ensures validated, repeatable cleaning every time.

Also read:

How Commercial Cleaning Machines Save Time & Boost Hygiene Standards

Image source: elements.envato.com

Filed Under: Manufacturing Tagged With: Health and Safety, manufacturing

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